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Article

Chromatin opening of DNA satellites by targeted sequence-specific drugs.

Molecular cell - 1 Nov 2000

Janssen S, Durussel T, Laemmli U K

Abstract excerpt

There are few tools available for dissecting and elucidating the functions of DNA satellites and other nongenic DNA. To address this, we have explored the experimental potential of DNA sequence-specific drugs containing pyrrole and imidazole amino acids (polyamides). Compounds were synthesized that target different Drosophila melanogaster satellites. Dimeric oligopyrroles were shown to target the AT-rich...

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PMID: 11106740
DOI: 10.1016/s1097-2765(00)00099-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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