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Article

Improved genotyping vaccine and wild-type poliovirus strains by restriction fragment length polymorphism analysis: clinical diagnostic implications.

Journal of clinical microbiology - 1 Dec 2000

Georgopoulou A, Markoulatos P, Spyrou N, Vamvakopoulos N C

Abstract excerpt

The combination of preventive vaccination and diagnostic typing of viral isolates from patients with clinical poliomyelitis constitutes our main protective shield against polioviruses. The restriction fragment length polymorphism (RFLP) adaptation of the reverse transcriptase (RT)-PCR methodology has advanced diagnostic genotyping of polioviruses, although further improvements are definitely needed. We report...

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Identifiers

PMID: 11101561
DOI: 10.1128/JCM.38.12.4337-4342.2000
PMCID: PMC87602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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