Article
Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi - 1 Jan 2000
Chen W C, Tsai F J, Wu J Y, Shi Y R, Wu H C
Abstract excerpt
The search for genes responsible for the abnormal development of the left-right (L/R) asymmetry has been conducted but no definite results have been reported. Recently, two human homologus mouse lefty1 genes, LEFTY A and LEFTY B, were analyzed for mutations in patients with the L/R anomalies. However, only two mutations were found in a survey of 126 patients. We collected genomic DNA from 10 children with Ivemark...
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