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Apolipoprotein E Gene Polymorphism And Its Effect On Plasma Lipids In Arteriosclerosis

1 Jan 2013

Abstract excerpt

BACKGROUND & OBJECTIVES: Myocardial infarction and stroke are leading causes of death worldwide. Primarily, arteriosclerosis is responsible for these events. There is a strong family history suggesting a genetic cause. Apolipoprotein E (apo E) plays an important role in lipid metabolism. Apo E is polymorphic with three isoforms, ApoE2, ApoE3 and ApoE4; which translate into three alleles of the gene. Its...

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PMID: 24298461
DOI: 10.7860/jcdr/2013/6195.3455

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