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Article

Identification of thromboxane synthase amino acid residues involved in heme-propionate binding.

Archives of biochemistry and biophysics - 1 Nov 2000

Hsu P Y, Tsai A L, Wang L H

Abstract excerpt

Thromboxane A2 synthase (TXAS) is a member of the cytochrome P450 superfamily and catalyzes an isomerization reaction that converts prostaglandin H2 to thromboxane A2. As a step toward understanding the structure/function relationships of TXAS, we mutated amino acid residues predicted to bind the...

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PMID: 11097184
DOI: 10.1006/abbi.2000.2041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11097184-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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