Article
Probing ligand binding to thromboxane synthase.
Biochemistry - 12 Feb 2013
Chao Wei-Chih, Lu Jyh-Feng, Wang Jinn-Shyan, Yang Hsiao-Ching, Pan Tai-An, Chou Steven Chun-Wei, Wang Lee-Ho, Chou Pi-Tai
Abstract excerpt
Various fluorescence experiments and computer simulations were utilized to gain further understanding of thromboxane A(2) synthase (TXAS), which catalyzes an isomerization of prostaglandins H(2) to give rise to thromboxane A(2) along with a fragmentation reaction to 12-L-hydroxy-5,8,10-heptadecat...
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