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Article

Haplotype evolution and linkage disequilibrium: A simulation study.

Human heredity - 1 Jan 2001

Calafell F, Grigorenko E L, Chikanian A A, Kidd K K

Abstract excerpt

We simulated the evolution of a three-site haplotype system, two restriction fragment length polymorphisms flanking one short tandem repeat polymorphism, under five different demographic scenarios, three with constant population size and two with population growth. The simulation was designed to observe the effects of population history, recombination fraction, and mutation rate on allele and haplotype...

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Identifiers

PMID: 11096275
DOI: 10.1159/000022963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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