Article
Intact MutY and its catalytic domain differentially contact with A/8-oxoG-containing DNA.
Nucleic acids research - 1 Dec 2000
Li X, Lu A L
Abstract excerpt
Escherichia coli MutY is an adenine and a weak guanine DNA glycosylase active on DNA substrates containing A/G, A/8-oxoG, A/C or G/8-oxoG mismatches. A truncated form of MutY (M25, residues 1-226) retains catalytic activity; however, the C-terminal domain of MutY is required for specific binding...
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