Article
Larger intercellular variation in (Q/R) editing of GluR6 than GluR5 revealed by single cell RT-PCR.
Neuroreport - 9 Nov 2000
Christensen K V, Dai W M, Lambert J D, Egebjerg J
Abstract excerpt
RNA editing of the pre-mRNA encoding the kainate receptor subtypes determines the Ca2+ permeability and the rectifying properties of the receptors in which these are assembled. GluR6 pre-mRNA contains three characterized editing sites: Q/R, IN and the Y/C, whereas GluR5 pre-mRNA contains only the (Q/R) site. Single cell RT-PCR was used on cultured cortical neurons to determine the relative expression and editing...
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