Article
SSCP is not so difficult: the application and utility of single-stranded conformation polymorphism in evolutionary biology and molecular ecology.
Molecular ecology - 1 Nov 2000
Sunnucks P, Wilson A C, Beheregaray L B, Zenger K, French J, Taylor A C
Abstract excerpt
All genetic markers are estimators of DNA nucleotide sequence variation. Rather than obtaining DNA sequence data, it is cheaper and faster to use techniques that estimate sequence variation, although this usually results in the loss of some information. SSCP (single-stranded conformation polymorphism) offers a sensitive but inexpensive, rapid, and convenient method for determining which DNA samples in a set...
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