Article
The Tetrahymena p80/p95 complex is required for proper telomere length maintenance and micronuclear genome stability.
Molecular cell - 1 Oct 2000
Miller M C, Collins K
Abstract excerpt
The telomerase enzyme adds simple sequence repeats to chromosome ends. Telomerases share two essential subunits, telomerase RNA and telomerase reverse transcriptase, that associate with species-specific proteins of predominantly unknown functions. The Tetrahymena p80/p95 complex can coimmunopurify active telomerase from cell extract, and recombinant p80/p95 can interact directly with telomerase RNA and...
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