Article
Equine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence.
Journal of virology - 1 Jul 2015
Feng Kurtis H, Gonzalez Gaelle, Deng Lingquan, Yu Hai, Tse Victor L, Huang Lu, Huang Kai, Wasik Brian R, Zhou Bin, Wentworth David E, Holmes Edward C, Chen Xi, Varki Ajit, Murcia Pablo R, Parrish Colin R
Abstract excerpt
UNLABELLED: The A/H3N8 canine influenza virus (CIV) emerged from A/H3N8 equine influenza virus (EIV) around the year 2000 through the transfer of a single virus from horses to dogs. We defined and compared the biological properties of EIV and CIV by examining their genetic variation, infection, and growth in different cell cultures, receptor specificity, hemagglutinin (HA) cleavage, and infection and growth in...
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