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Article

Restless legs syndrome in monozygotic twins: clinical correlates.

Neurology - 14 Nov 2000

Ondo W G, Vuong K D, Wang Q

Abstract excerpt

To better understand genetic characteristics of restless legs syndrome (RLS) and identify nongenetic factors that may influence phenotype, the authors studied 12 identical twins in which at least one member expressed RLS. Ten of the 12 twin pairs were concordant for RLS symptoms. Despite the high concordance rate, the disease severity, age at onset, and symptom descriptions often varied between twins. Birth...

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Identifiers

PMID: 11087794
DOI: 10.1212/wnl.55.9.1404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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