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Article

Effect of venlafaxine on imipramine metabolism.

Psychiatry research - 20 Nov 2000

Albers L J, Reist C, Vu R L, Fujimoto K, Ozdemir V, Helmeste D, Poland R, Tang S W

Abstract excerpt

The present study was designed to determine the effect of venlafaxine on imipramine metabolism in an attempt to elucidate the potential for cytochrome P450 drug-drug interactions with venlafaxine. We examined the metabolism of a single 100-mg dose of imipramine before and after treatment with venlafaxine, 50 mg three times a day. Eight male subjects were phenotyped for CYP2D6 activity. Two subjects were poor...

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Source

Identifiers

PMID: 11084219
DOI: 10.1016/s0165-1781(00)00213-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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