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Article

Paired Ig-like receptor homologs in birds and mammals share a common ancestor with mammalian Fc receptors

14 Nov 2000

Abstract excerpt

Paired Ig-like receptors (PIR) that can reciprocally modulate cellular activation have been described in mammals. In the present study, we searched expressed sequence tag databases for PIR relatives to identify chicken expressed sequence tags predictive of approximately 25% amino acid identity to mouse PIR. Rapid amplification of cDNA ends (RACE)-PCR extension of expressed sequence-tag sequences using chicken...

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PMID: 11078516
DOI: 10.1073/pnas.230442897

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