Article
Zuotin, a ribosome-associated DnaJ molecular chaperone.
The EMBO journal - 17 Aug 1998
Yan W, Schilke B, Pfund C, Walter W, Kim S, Craig E A
Abstract excerpt
Correct folding of newly synthesized polypeptides is thought to be facilitated by Hsp70 molecular chaperones in conjunction with DnaJ cohort proteins. In Saccharomyces cerevisiae, SSB proteins are ribosome-associated Hsp70s which interact with the newly synthesized nascent polypeptide chain. Here we report that the phenotypes of an S.cerevisiae strain lacking the DnaJ-related protein Zuotin (Zuo1) are very...
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