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Article

Impaired vascular contractility and blood pressure homeostasis in the smooth muscle alpha-actin null mouse.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2000

Schildmeyer L A, Braun R, Taffet G, Debiasi M, Burns A E, Bradley A, Schwartz R J

Abstract excerpt

The smooth muscle (SM) alpha-actin gene activated during the early stages of embryonic cardiovascular development is switched off in late stage heart tissue and replaced by cardiac and skeletal alpha-actins. SM alpha-actin also appears during vascular development, but becomes the single most abundant protein in adult vascular smooth muscle cells. Tissue-specific expression of SM alpha-actin is thought to be...

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PMID: 11053242
DOI: 10.1096/fj.99-0927com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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