Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB.

Chemistry & biology - 1 Aug 2000

Kays A R, Schepartz A

Abstract excerpt

BACKGROUND: The TATA box binding protein (TBP) is required by all three RNA polymerases for the promoter-specific initiation of transcription. All eukaryotic TBP-DNA complexes observed in crystal structures show the conserved C-terminal domain of TBP (TBPc) bound to the TATA box in a single orientation that is consistent with assembly of a preinitiation complex (PIC) possessing a unique polarity. The binding of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Deoxyribonuclease I
Share to DNA Footprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Holoenzymes

Share to RNA Polymerase II

Share to TATA Box

Share to TATA-Box Binding Protein

Share to Transcription Factor TFIIB

Source

Identifiers

PMID: 11048951
DOI: 10.1016/s1074-5521(00)00009-0

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB.PMID 11048951Read ↗

The symmetry of the yeast U6 RNA gene's TATA box and the orientation of the TATA-binding protein in yeast TFIIIB.Semantic proximity Read ↗

Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes.Semantic proximity Read ↗

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.Semantic proximity Read ↗

A TATA binding protein mutant with increased affinity for DNA directs transcription from a reversed TATA sequence in vivo.Semantic proximity Read ↗

The Saccharomyces cerevisiae RNA polymerase III recruitment factor subunits Brf1 and Bdp1 impose a strict sequence preference for the downstream half of the TATA box.Semantic proximity Read ↗

Role of TATA box sequence and orientation in determining RNA polymerase II/III transcription specificity.Semantic proximity Read ↗

SAGA mediates transcription from the TATA-like element independently of Taf1p/TFIID but dependent on core promoter structures in Saccharomyces cerevisiae.Semantic proximity Read ↗

Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.Semantic proximity Read ↗

A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration.Semantic proximity Read ↗

A histone fold TAF octamer within the yeast TFIID transcriptional coactivator.Semantic proximity Read ↗

Enhancement of TBP binding by activators and general transcription factors.Semantic proximity Read ↗

Sequence-dependent solution structure and motions of 13 TATA/TBP (TATA-box binding protein) complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.