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Article

Long-term therapeutic drug monitoring of clozapine and metabolites in psychiatric in- and outpatients.

Psychopharmacology - 1 Sept 2000

Dettling M, Sachse C, Brockmöller J, Schley J, Müller-Oerlinghausen B, Pickersgill I, Rolfs A, Schaub R T, Schmider J

Abstract excerpt

RATIONALE: Clozapine is a unique antipsychotic drug, outstanding for its lack of extrapyramidal side-effects and its superior efficacy in refractory schizophrenia. However, an unambiguous concentration-response relationship has not yet been established. OBJECTIVE: We investigated serum concentrations of clozapine, norclozapine and clozapine-N-oxide in psychiatric in- and outpatients to identify particular...

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Source

Identifiers

PMID: 11041319
DOI: 10.1007/s002130000503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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