Article
The IL9R region contribution in asthma is supported by genetic association in an isolated population.
European journal of human genetics : EJHG - 1 Oct 2000
Kauppi P, Laitinen T, Ollikainen V, Mannila H, Laitinen L A, Kere J
Abstract excerpt
Interleukin 9 (IL9) is involved in mast cell maturation and the enhancement of IgE production by B cells. Furthermore, linkage data in human and mice have suggested that IL9 may contribute to asthma. Since our genetic analysis of the 5q cytokine cluster did not support a genetic role for the IL9 gene, we became interested in the IL9 receptor gene (IL9R) in the pseudoautosomal region. We genotyped markers sDF2 and...
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