Trinucleotide repeats in the human genome: size distributions for all possible triplets and detection of expanded disease alleles in a group of Huntington disease individuals by the repeat expansion detection method.

doi:10.1093/hmg/6.1.77

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Article

Trinucleotide repeats in the human genome: size distributions for all possible triplets and detection of expanded disease alleles in a group of Huntington disease individuals by the repeat expansion detection method.

Human molecular genetics - 1 Jan 1997

Hofferbert S, Schanen N C, Chehab F, Francke U

Abstract excerpt

Using a modified Repeat Expansion Detection (RED) assay, that was optimized for individual oligonucleotides, unrelated individuals were systematically screened for maximal repeat sizes of each of the ten possible trinucleotide repeats. Cloned trinucleotide repeats were generated and used as stand...

Topics

Adult
Alleles
Cell Line
Female
Gene Frequency
Genome, Human
Humans
Huntington Disease
In Situ Hybridization
Male
Sensitivity and Specificity
Trinucleotide Repeats

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Open in PubMed

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PMID: 9002673
DOI: 10.1093/hmg/6.1.77

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9002673-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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