Article
Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs.
Arthritis and rheumatism - 1 Oct 2000
Prahalad S, Ryan M H, Shear E S, Thompson S D, Giannini E H, Glass D N
Abstract excerpt
OBJECTIVE: To test for linkage between the HLA region and juvenile rheumatoid arthritis (JRA), with stratification by onset and course types, in a cohort of affected sibling pairs (ASPs). METHODS: Eighty pairs of siblings with JRA who were registered with the Research Registry for JRA ASPs (sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases) were typed for HLA-DR. The observed...
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