Article
Function of human mitochondrial 2,4-dienoyl-CoA reductase and rat monofunctional Delta3-Delta2-enoyl-CoA isomerase in beta-oxidation of unsaturated fatty acids.
The Biochemical journal - 15 Dec 1999
Gurvitz A, Wabnegger L, Yagi A I, Binder M, Hartig A, Ruis H, Hamilton B, Dawes I W, Hiltunen J K, Rottensteiner H
Abstract excerpt
Human 2,4-dienoyl-CoA reductase (2,4-reductase; DECR) and rat monofunctional Delta(3)-Delta(2)-enoyl-CoA isomerase (rat 3, 2-isomerase; ECI) are thought to be mitochondrial auxiliary enzymes involved in the beta-oxidation of unsaturated fatty acids. However, their function during this process has not been demonstrated. Although they lack obvious peroxisomal targeting signals (PTSs), both proteins have been...
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