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Article

Peroxisomal Delta3-cis-Delta2-trans-enoyl-CoA isomerase encoded by ECI1 is required for growth of the yeast Saccharomyces cerevisiae on unsaturated fatty acids.

The Journal of biological chemistry - 20 Nov 1998

Gurvitz A, Mursula A M, Firzinger A, Hamilton B, Kilpeläinen S H, Hartig A, Ruis H, Hiltunen J K, Rottensteiner H

Abstract excerpt

We have identified the Saccharomyces cerevisiae gene ECI1 encoding Delta3-cis-Delta2-trans-enoyl-CoA isomerase that acts as an auxiliary enzyme in the beta-oxidation of (poly)unsaturated fatty acids. A mutant devoid of Eci1p was unable to grow on media containing unsaturated fatty acids such as o...

Topics

3-Hydroxyacyl CoA Dehydrogenases
Amino Acid Sequence
Catalytic Domain
Cell Compartmentation
Conserved Sequence
Enoyl-CoA Hydratase
Enzyme Induction
Fatty Acids, Unsaturated
Genes, Fungal
Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isomerases

Isomerism

Luminescent Proteins

Microbodies

Multienzyme Complexes

Mutation

Oleic Acid

Palmitic Acid

Source

Identifiers

PMID: 9813046
DOI: 10.1074/jbc.273.47.31366

Genes

ECI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9813046-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Peroxisomal Delta3-cis-Delta2-trans-enoyl-CoA isomerase encoded by ECI1 is required for growth of the yeast Saccharomyces cerevisiae on unsaturated fatty acids.PMID 9813046Read ↗

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