Article
A SNP resource for human chromosome 22: extracting dense clusters of SNPs from the genomic sequence.
Genome research - 1 Jan 2001
Dawson E, Chen Y, Hunt S, Smink L J, Hunt A, Rice K, Livingston S, Bumpstead S, Bruskiewich R, Sham P, Ganske R, Adams M, Kawasaki K, Shimizu N, Minoshima S, Roe B, Bentley D, Dunham I
Abstract excerpt
The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of 12,267 potential variants (SNPs and other small insertions/deletions) of human chromosome 22, discovered in the overlaps of 460 clones used for the chromosome sequencing. We found, on average, 1 potential variant every...
Topics
- Base Composition
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- DNA Transposable Elements
- Genetic Variation
- Genome, Human
- Humans
- Polymorphism, Single Nucleotide
- Reproducibility of Results