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Quantification of mtDNA in single oocytes, polar bodies and subcellular components by real-time rapid cycle fluorescence monitored PCR

1 Aug 2000

Abstract excerpt

Oocytes, in general, are greatly enriched in mitochondria to support higher rates of macromolecular synthesis and critical physiological processes characteristic of early development. An inability of these organelles to amplify and/or to accumulate ATP has been linked to developmental abnormality or arrest. The number of mitochondrial genomes present in mature mouse and human metaphase II oocytes was estimated by...

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PMID: 11014500
DOI: 10.1017/s0967199400001003

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Source receipt: pubmed, retrieved 7 Sept 2026.

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