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Article

The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator.

The Journal of physiology - 15 Jun 2013

Bannister John P, Leo Marie Dennis, Narayanan Damodaran, Jangsangthong Wanchana, Nair Anitha, Evanson Kirk W, Pachuau Judith, Gabrick Kyle S, Boop Frederick A, Jaggar Jonathan H

Abstract excerpt

Voltage-dependent L-type Ca(2+) channels (CaV1.2) are the primary Ca(2+) entry pathway in vascular smooth muscle cells (myocytes). CaV1.2 channels control systemic blood pressure and organ blood flow and are pathologically altered in vascular diseases, which modifies vessel contractility. The CaV...

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Source

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Identifiers

PMID: 23568894
DOI: 10.1113/jphysiol.2013.251926
PMCID: PMC3832115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23568894-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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