Article
Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources.
Molecular immunology - 1 Dec 1994
Jung W, Krueger S, Renner C, Gause A, Sahin U, Trümper L, Pfreundschuh M
Abstract excerpt
CD30L, the ligand for the activation antigen CD30, is a member of the tumor necrosis factor family of cytokines. Binding of CD30L to CD30, which is a member of the nerve growth factor/tumor necrosis factor receptor family, induces proliferation in peripheral blood lymphocytes and Hodgkin's derived cell lines with a T-cell phenotype such as HDLM-2 and L540, while cell lines derived from anaplastic large cell...
Topics
- Base Sequence
- CD30 Ligand
- Calcium
- Cloning, Molecular
- Genomic Library
- Humans
- Ki-1 Antigen
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Open Reading Frames