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Article

Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease.

Infection and immunity - 1 Feb 2002

Jarraud Sophie, Mougel Christophe, Thioulouse Jean, Lina Gerard, Meugnier Hélène, Forey Françoise, Nesme Xavier, Etienne Jerome, Vandenesch François

Abstract excerpt

The expression of most Staphylococcus aureus virulence factors is controlled by the agr locus, which encodes a two-component signaling pathway whose activating ligand is an agr-encoded autoinducing peptide (AIP). A polymorphism in the amino acid sequence of the AIP and of its corresponding receptor divides S. aureus strains into four major groups. Within a given group, each strain produces a peptide that can...

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Identifiers

PMID: 11796592
DOI: 10.1128/IAI.70.2.631-641.2002
PMCID: PMC127674

Genes

AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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