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Evolutionary Genetics of the Accessory Gene Regulator ( <i>agr</i> ) Locus in <i>Staphylococcus aureus</i>

1 Dec 2005

Abstract excerpt

The accessory gene regulator (agr) locus influences the expression of many virulence genes in the human pathogen Staphylococcus aureus. Four allelic groups of agr, which generally inhibit the regulatory activity of each other, have been identified within the species. Interference in virulence gene expression caused by different agr groups has been suggested to be a mechanism for isolating bacterial populations...

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PMID: 16321935
DOI: 10.1128/jb.187.24.8312-8321.2005

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