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Article

The Ephx1(d) allele encoding an Arg338Cys substitution is associated with heat lability.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2000

Hartsfield J K, Everett E T

Abstract excerpt

Heat lability of the mouse hepatic microsomal epoxide hydrolase 1 enzyme-specific activity (EC 3.3.2.3) is greater for the A/J than the C57BL/6J strain. Analysis of the microsomal epoxide hydrolase 1 cDNA coding sequences shows the C57BL/6J and A/J strains to differ in a single base, a C to T transition at position 1012 from the ATG. This change would predict a substitution of an Arg for a Cys at codon 338. Lyman...

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PMID: 11003708
DOI: 10.1007/s003350010169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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