Article
Activation of L-type calcium channels induces corticotropin-releasing factor secretion from human placental trophoblasts.
The Journal of clinical endocrinology and metabolism - 1 Sept 2000
Robidoux J, Simoneau L, Masse A, Lafond J
Abstract excerpt
The ultimate outcome of pregnancy, parturition, is a well orchestrated process in which placental corticotropin-releasing factor (CRF) seems to play an important role. The objective of the present study was to investigate the involvement of L-type calcium channels and calcium-dependent signaling in the depolarization-induced CRF release from human syncytiotrophoblast. The basal secretion of CRF by trophoblastic...
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