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Article

Human Chorionic Gonadotrophin Relaxation of Human Pregnant Myometrium and Activation of the BKCaChannel

1 Sept 2003

Abstract excerpt

The uterorelaxant effect of human chorionic gonadotropin (hCG) is regarded as an important mediator in maintenance of uterine quiescence during pregnancy with clinical potential for tocolysis, the mechanisms of which are unknown. The large conductance calcium-activated K(+) channel (BK(Ca)) is ubiquitously encountered in human uterine tissue and plays a significant role in modulating myometrial cell membrane...

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Identifiers

PMID: 12970303
DOI: 10.1210/jc.2003-030221

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