Mechanical Stretch Up-Regulates the Human Oxytocin Receptor in Primary Human Uterine Myocytes

Abstract excerpt

Oxytocin receptor (OTR) expression is increased before the onset of labor in all models of parturition. However, the mechanisms responsible for the increase in OTR expression are uncertain. Animal data suggest that uterine stretch increases OTR mRNA expression. In primary cultures of human uterine smooth muscle cells obtained from nonpregnant (NP) women and pregnant women before (NL) and after (L) the onset of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neuroendocrine regulation and behavior
• Share to Preterm Birth and Chorioamnionitis
• Share to Reproductive System and Pregnancy