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Article

The C677T polymorphism of the methylenetetrahydrofolate reductase gene in Mexican mestizo neural-tube defect parents, control mestizo and native populations.

Annales de genetique - 1 Jan 2000

Dávalos I P, Olivares N, Castillo M T, Cantú J M, Ibarra B, Sandoval L, Morán M C, Gallegos M P, Chakraborty R, Rivas F

Abstract excerpt

The C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene, associated with the thermolabile form of the enzyme, has reportedly been found to be increased in neural-tube defects (NTD), though this association is still unclear. A group of 107 mestizo parents of NTD children and five control populations: 101 mestizo (M), 50 Huichol (H), 38 Tarahumara (T), 21 Purepecha (P) and 20 Caucasian (C)...

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Source

Identifiers

PMID: 10998450
DOI: 10.1016/s0003-3995(00)90012-1

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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