MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas.

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Article

MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas.

Blood - 1 Mar 1991

Ladanyi M, Offit K, Jhanwar S C, Filippa D A, Chaganti R S

Abstract excerpt

The configuration of the MYC gene in diffuse large cell lymphomas (DLCL) with translocations involving band 8q24 [t(8q24)] has not been systematically studied. We collected cytogenetic and clinical data on 171 consecutive cases of DLCL, including cleaved, noncleaved, and immunoblastic types, of w...

Topics

Adult
Blotting, Southern
Chromosomes, Human, Pair 8
Deoxyribonucleases, Type II Site-Specific
Exons
Female
Gene Rearrangement
Humans
Lymphoma, Large B-Cell, Diffuse
Male
Middle Aged
Mutation
Polymorphism, Restriction Fragment Length
Proto-Oncogene Proteins c-myc
Restriction Mapping
Translocation, Genetic

Source

Open in PubMed

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PMID: 1671647

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1671647-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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