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Article

Gallium Disrupts Iron Metabolism of Mycobacteria Residing within Human Macrophages

1 Oct 2000

Abstract excerpt

Mycobacterium tuberculosis and M. avium complex (MAC) enter and multiply within monocytes and macrophages in phagosomes. In vitro growth studies using standard culture media indicate that siderophore-mediated iron (Fe) acquisition plays a critical role in the growth and metabolism of both M. tuberculosis and MAC. However, the applicability of such studies to conditions within the macrophage phagosome is unclear,...

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PMID: 10992462
DOI: 10.1128/iai.68.10.5619-5627.2000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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