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Article

Association study between immune-related miRNAs and mixed connective tissue disease.

Arthritis research & therapy - 11 Jan 2021

Stypińska Barbara, Lewandowska Aleksandra, Felis-Giemza Anna, Olesińska Marzena, Paradowska-Gorycka Agnieszka

Abstract excerpt

BACKGROUND: Mixed connective tissue disease (MCTD) is a rare condition that is distinguished by the presence of specific U1-RNP antibodies. Information about its etiopathology and diagnostics is still unclear. miRNAs such as miR-146, miR-155, and miR-143 emerged as key regulators of the immune system, known to be involved in the development of autoimmune diseases and cancers. We performed an association study...

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Identifiers

PMID: 33430976
DOI: 10.1186/s13075-020-02403-9
PMCID: PMC7802256

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