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Article

Anti-SMN autoantibodies in mixed connective tissue disease are associated with a severe systemic sclerosis phenotype.

RMD open - 1 Oct 2023

El Kamouni Hajar, S Jalaledin Darya, Albert Alexandra, Hoa Sabrina, Vo Caroline, Bourré-Tessier Josiane, Rich Éric, Goulet Jean-Richard, Koenig Martial, Pérez Gemma, Choi May Y, Troyanov Yves, Satoh Minoru, Fritzler Marvin J, Senécal Jean-Luc, Landon-Cardinal Océane

Abstract excerpt

OBJECTIVES: The survival of motor neuron (SMN) complex has an essential role in the assembly of small nuclear ribonucleoproteins (RNP). Recent reports have described autoantibodies (aAbs) to the SMN complex as novel biomarkers in anti-U1RNP+ myositis patients. The aim of this study was to compare phenotypic features of anti-U1RNP+ mixed connective tissue disease (MCTD) patients with and without anti-SMN aAbs....

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Identifiers

PMID: 37797966
DOI: 10.1136/rmdopen-2023-003431
PMCID: PMC10551952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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