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The Paramyxovirus Simian Virus 5 V Protein Slows Progression of the Cell Cycle

1 Oct 2000

Abstract excerpt

Infection of cells by many viruses affects the cell division cycle of the host cell to favor viral replication. We examined the ability of the paramyxovirus simian parainfluenza virus 5 (SV5) to affect cell cycle progression, and we found that SV5 slows the rate of proliferation of HeLa T4 cells. The SV5-infected cells had a delayed transition from G(1) to S phase and prolonged progression through S phase, and...

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PMID: 10982362
DOI: 10.1128/jvi.74.19.9152-9166.2000

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