Are fasting plasma homocyst(e)ine levels heritable? A study of normotensive twins.

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Article

Are fasting plasma homocyst(e)ine levels heritable? A study of normotensive twins.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Sept 2000

Cesari M, Burlina A B, Narkiewicz K, Sartori M T, Sacchetto A, Rossi G P

Abstract excerpt

BACKGROUND: Plasma homocyst(e)ine levels (pHo) can be a risk marker for cardiovascular diseases. Different factors affect pHo, but it remains unclear whether pHo are genetically determined and whether they are related to other risk markers, such as the angiotensin I converting enzyme (ACE) and the plasminogen activator inhibitor type-1 (PAI-1). METHODS: We measured fasting pHo, plasma levels of ACE (pACE), and...

Topics

Adult
DNA
Fasting
Female
Genetic Predisposition to Disease
Homocysteine
Humans
Male
Peptidyl-Dipeptidase A
Plasminogen Activator Inhibitor 1
Polymerase Chain Reaction
Twins, Dizygotic
Twins, Monozygotic

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Open in PubMed

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PMID: 10979240

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