Article
Estimates of heritability of plasma homocyst(e)ine levels in aging adult male twins.
Clinical genetics - 1 Jun 1991
Reed T, Malinow M R, Christian J C, Upson B
Abstract excerpt
Plasma homocyst(e)ine level was determined for 96 identical (MZ) and 92 fraternal (DZ) adult male twins aged 59-69. There was no difference in mean between MZ (10.31 nmol/ml) and DZ (10.36 nmol/ml) twins. The intraclass correlation coefficient of the log-transformed homocyst(e)ine level in 43 complete MZ and 39 complete DZ pairs was 0.55 and 0.19, respectively. The MZ correlation was significantly (p less than...
Topics
- Aged
- Cardiovascular Diseases
- Genetic Variation
- Homocysteine
- Humans
- Longitudinal Studies
- Male
- Middle Aged
- Risk Factors
- Twins, Dizygotic
- Twins, Monozygotic
- Veterans