Increased circulating levels of plasma ATP in cystic fibrosis patients.

doi:10.1046/j.1365-2281.2000.00272.x

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Article

Increased circulating levels of plasma ATP in cystic fibrosis patients.

Clinical physiology (Oxford, England) - 1 Sept 2000

Lader A S, Prat A G, Jackson G R, Chervinsky K L, Lapey A, Kinane T B, Cantiello H F

Abstract excerpt

Recent studies have shown that the cystic fibrosis transmembrane conductance regulator (CFTR), an ATP-binding cassette (ABC) transporter whose mutations are responsible for cystic fibrosis (CF), permeates ATP. However, little information is available concerning extracellular ATP concentrations in CF patients. Thus, the goal of this preliminary study was to determine the circulating levels of plasma ATP in CF...

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