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Article

Hic, a novel surface protein of Streptococcus pneumoniae that interferes with complement function.

The Journal of biological chemistry - 24 Nov 2000

Janulczyk R, Iannelli F, Sjoholm A G, Pozzi G, Bjorck L

Abstract excerpt

The important human pathogen Streptococcus pneumoniae was found to absorb factor H, an inhibitor of complement, from human plasma. We identified the gene encoding a novel surface protein, factor H-binding inhibitor of complement (Hic), in the pspC locus of type 3 pneumococci. Unlike PspC proteins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10967103
DOI: 10.1074/jbc.M004572200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10967103-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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