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Article

Induction of the BRCA2 promoter by nuclear factor-kappa B.

The Journal of biological chemistry - 10 Nov 2000

Wu K, Jiang S W, Thangaraju M, Wu G, Couch F J

Abstract excerpt

BRCA2 is a tumor suppressor gene that has been implicated in response to DNA damage, cell cycle control, and transcription. BRCA2 has been found to be overexpressed in many breast tumors, suggesting that altered expression of the BRCA2 gene may contribute to breast tumorigenesis. To determine how BRCA2 is overexpressed in tumors, we investigated the transcriptional regulation of the BRCA2 promoter. Deletion...

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Source

Identifiers

PMID: 10961992
DOI: 10.1074/jbc.M004390200

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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