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Article

HIV type 1 protease cleavage site mutations and viral fitness: implications for drug susceptibility phenotyping assays.

AIDS research and human retroviruses - 10 Aug 2000

Robinson L H, Myers R E, Snowden B W, Tisdale M, Blair E D

Abstract excerpt

The recombinant virus assay (RVA) is a method for assessing the susceptibility of human immunodeficiency virus type 1 (HIV-1) plasma isolates to antiretroviral drugs. The RVA involves the production of viable virus in vitro by homologous recombination of RT-PCR products from plasma virus with a noninfectious reverse transcriptase (RT) or protease (PR)-deleted cloned HIV-1 provirus. In this study, we have...

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Identifiers

PMID: 10954890
DOI: 10.1089/088922200414992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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