Article
Meiotic double-strand breaks in Schizosaccharomyces pombe.
Current genetics - 1 Jul 2000
Zenvirth D, Simchen G
Abstract excerpt
Meiotic DNA double-strand breaks (DSBs) are associated with recombination hot spots in the yeast Saccharomyces cerevisiae and are believed to initiate the process of recombination. Until now, meiosis-induced breaks have not been shown to occur regularly in other organisms. Here we show, by pulsed-field gel electrophoresis of DNA, that meiotic DSBs occur transiently in all three chromosomes of the fission yeast...
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