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Adherence of<i>Staphylococcus aureus</i>to Endothelial Cells: Influence of Capsular Polysaccharide, Global Regulator<i>agr</i>, and Bacterial Growth Phase

1 Sept 2000

Abstract excerpt

The adherence of Staphylococcus aureus to human endothelial cells (EC) is probably an important step in the pathogenesis of systemic staphylococcal infections. We examined the influence of type 5 capsular polysaccharide (CP5) production, the global regulator agr, and the bacterial growth phase on S. aureus adherence to EC. Whereas S. aureus Newman showed maximal adherence to EC in the logarithmic phase of growth,...

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PMID: 10948098
DOI: 10.1128/iai.68.9.4865-4871.2000

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