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Article

The variome of pneumococcal virulence factors and regulators.

BMC genomics - 3 Jan 2018

Gámez Gustavo, Castro Andrés, Gómez-Mejia Alejandro, Gallego Mauricio, Bedoya Alejandro, Camargo Mauricio, Hammerschmidt Sven

Abstract excerpt

BACKGROUND: In recent years, the idea of a highly immunogenic protein-based vaccine to combat Streptococcus pneumoniae and its severe invasive infectious diseases has gained considerable interest. However, the target proteins to be included in a vaccine formulation have to accomplish several genetic and immunological characteristics, (such as conservation, distribution, immunogenicity and protective effect), in...

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Identifiers

PMID: 29298677
DOI: 10.1186/s12864-017-4376-0
PMCID: PMC5753484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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