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Isolation of a novel gene on 8p21.3–22 whose expression is reduced significantly in human colorectal cancers with liver metastasis

21 Jul 2000

Abstract excerpt

Metastasis, a major factor contributing to poor prognosis of cancer patients, is caused by a complex series of events that involve many genes. To investigate this process, we analyzed by differential display three cell lines that had been established from a murine colon adenocarcinoma (colon 26), NL4, NL17, and NL22, each of which possessed a different potential for metastasis in mice. We report here the...

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PMID: 10918388
DOI: 10.1002/1098-2264(2000)9999:9999<::aid-gcc1001>3.0.co;2-#

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